Cancers, Free Full-Text
-
By A Mystery Man Writer
-
-
4.5(302)
![Cancers, Free Full-Text](https://www.mdpi.com/cancers/cancers-13-02277/article_deploy/html/images/cancers-13-02277-g001.png)
Product Description
Melanoma is one of the most aggressive skin cancers with a sharp rise in incidence in the last decades, especially in young people. Recognized as a significant public health issue, melanoma is studied with increasing interest as new discoveries in molecular signaling and receptor modulation unlock innovative treatment options. Stress exposure is recognized as an important component in the immune-inflammatory interplay that can alter the progression of melanoma by regulating the release of neuroendocrine factors. Various neurotransmitters, such as catecholamines, glutamate, serotonin, or cannabinoids have also been assessed in experimental studies for their involvement in the biology of melanoma. Alpha-MSH and other neurohormones, as well as neuropeptides including substance P, CGRP, enkephalin, beta-endorphin, and even cellular and molecular agents (mast cells and nitric oxide, respectively), have all been implicated as potential factors in the development, growth, invasion, and dissemination of melanoma in a variety of in vitro and in vivo studies. In this review, we provide an overview of current evidence regarding the intricate effects of neuroendocrine factors in melanoma, including data reported in recent clinical trials, exploring the mechanisms involved, signaling pathways, and the recorded range of effects.
![Cancers, Free Full-Text](https://media.cancercare.org/page-headers/small-publications-img.webp)
Order Our Free Publications
![Cancers, Free Full-Text](https://res.cloudinary.com/teepublic/image/private/s--8r3iS75v--/c_crop,x_10,y_10/c_fit,w_992/c_crop,g_north_west,h_827,w_1127,x_-68,y_-82/l_misc:transparent_1260/fl_layer_apply,g_north_west,x_-134,y_-294/c_mfit,g_north_east,u_misc:tapestry-l-s-gradient/e_displace,fl_layer_apply,x_0,y_34/l_upload:v1507037315:production:blanks:uue6kkaylik55suzvwsb/fl_layer_apply,g_north_west,x_0,y_0/b_rgb:000000/c_limit,f_jpg,h_630,q_90,w_630/v1571919157/production/designs/6452735_0.jpg)
I Am Cancer Free! - Cancer Free Gift - Tapestry
![Cancers, Free Full-Text](https://res.cloudinary.com/teepublic/image/private/s--yedPjX_W--/c_crop,x_10,y_10/c_fit,w_830/c_crop,g_north_west,h_1038,w_1038,x_-104,y_-242/l_upload:v1565806151:production:blanks:vdbwo35fw6qtflw9kezw/fl_layer_apply,g_north_west,x_-215,y_-353/b_rgb:000000/c_limit,f_jpg,h_630,q_90,w_630/v1571919157/production/designs/6452735_0.jpg)
I Am Cancer Free! - Cancer Free Gift - Pin
![Cancers, Free Full-Text](https://www.thelancet.com/cms/asset/9f7c134d-31b6-46e1-bbc7-bf424da41e73/gr1.jpg)
Predicting peritoneal recurrence and disease-free survival from CT images in gastric cancer with multitask deep learning: a retrospective study - The Lancet Digital Health
Cancers, Free Full-Text, g1 f1
![Cancers, Free Full-Text](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-021-24994-w/MediaObjects/41467_2021_24994_Fig1_HTML.png)
Detection and characterization of lung cancer using cell-free DNA fragmentomes
![Cancers, Free Full-Text](https://img.freepik.com/free-psd/breast-cancer-awareness-editable-text-effect_47987-13695.jpg)
Free PSD Breast cancer awareness editable text effect
![Cancers, Free Full-Text](http://www.jshbps.jp/uploads/images/22-3.jpg)
Classification of biliary tract cancers established by JSHBPS: 3rd English edition|Japanese Society of Hepato-Biliary-Pancreatic Surgery
![Cancers, Free Full-Text](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41591-022-01746-x/MediaObjects/41591_2022_1746_Fig1_HTML.png)
The future of early cancer detection
![Cancers, Free Full-Text](https://www.creativefabrica.com/wp-content/uploads/2020/10/26/cancer-svg-cancer-survivor-svg-Graphics-6285746-1.png)
Cancer Svg, Cancer Survivor Svg Graphic by artinrhythm · Creative Fabrica
![Cancers, Free Full-Text](https://external-preview.redd.it/06sCBLm7kUvpbJS66BZQkYmlX3iwoIFSjeMHn8V3C64.jpg?auto=webp&s=4bad7696259e6fdab59dcbf297091f0276ee27aa)
Cancers, Free Full-Text
![Cancers, Free Full-Text](https://ih1.redbubble.net/image.5064257023.8565/fposter,small,wall_texture,square_product,600x600.jpg)